OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance

The forkhead transcription factor FOXM1 has a key role in DNA damage response, and its deregulated overexpression is associated with genotoxic drug resistance in breast cancer. However, little is known about the posttranslational mechanisms by which FOXM1 expression is regulated by genotoxic agents...

詳細記述

保存先:
書誌詳細
出版年:Oncogene
主要な著者: Karunarathna, U, Kongsema, M, Zona, S, Gong, C, Cabrera, E, Gomes, A R, Man, E P S, Khongkow, P, Tsang, J W-H, Khoo, U-S, Medema, R H, Freire, R, Lam, E W-F
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606987/
https://ncbi.nlm.nih.gov/pubmed/26148240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.208
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