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OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance
The forkhead transcription factor FOXM1 has a key role in DNA damage response, and its deregulated overexpression is associated with genotoxic drug resistance in breast cancer. However, little is known about the posttranslational mechanisms by which FOXM1 expression is regulated by genotoxic agents...
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| Опубликовано в: : | Oncogene |
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| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4606987/ https://ncbi.nlm.nih.gov/pubmed/26148240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.208 |
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