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Identification of disulfide cross-linked tau dimer responsible for tau propagation

Recent evidence suggests that tau aggregates are not only neurotoxic, but also propagate in neurons acting as a seed for native tau aggregation. Prion-like tau transmission is now considered as an important pathogenic mechanism driving the progression of tau pathology in the brain. However, prion-li...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Kim, Dohee, Lim, Sungsu, Haque, Md. Mamunul, Ryoo, Nayeon, Hong, Hyun Seok, Rhim, Hyewhon, Lee, Dong-Eun, Chang, Young-Tae, Lee, Jun-Seok, Cheong, Eunji, Kim, Dong Jin, Kim, Yun Kyung
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606741/
https://ncbi.nlm.nih.gov/pubmed/26470054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15231
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