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Identification of disulfide cross-linked tau dimer responsible for tau propagation
Recent evidence suggests that tau aggregates are not only neurotoxic, but also propagate in neurons acting as a seed for native tau aggregation. Prion-like tau transmission is now considered as an important pathogenic mechanism driving the progression of tau pathology in the brain. However, prion-li...
Guardado en:
| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4606741/ https://ncbi.nlm.nih.gov/pubmed/26470054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15231 |
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