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Longitudinal Assessment of Tau Pathology in Patients with Alzheimer’s Disease Using [(18)F]THK-5117 Positron Emission Tomography

The formation of neurofibrillary tangles is believed to contribute to the neurodegeneration observed in Alzheimer’s disease (AD). Postmortem studies have shown strong associations between the neurofibrillary pathology and both neuronal loss and the severity of cognitive impairment. However, the temp...

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Veröffentlicht in:PLoS One
Hauptverfasser: Ishiki, Aiko, Okamura, Nobuyuki, Furukawa, Katsutoshi, Furumoto, Shozo, Harada, Ryuichi, Tomita, Naoki, Hiraoka, Kotaro, Watanuki, Shoichi, Ishikawa, Yoichi, Tago, Tetsuro, Funaki, Yoshihito, Iwata, Ren, Tashiro, Manabu, Yanai, Kazuhiko, Kudo, Yukitsuka, Arai, Hiroyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604169/
https://ncbi.nlm.nih.gov/pubmed/26461913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140311
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