Dynamic PET Measures of Tau Accumulation in Cognitively Normal Older Adults and Alzheimer’s Disease Patients Measured Using [18F] THK-5351

BACKGROUND: [(18)F]THK5351, a recently-developed positron emission tomography (PET) tracer for measuring tau neurofibrillary tangle accumulation, may help researchers examine aging, disease, and tau pathology in living human brains. We examined THK5351 tracer pharmacokinetics to define an optimal ac...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lockhart, Samuel N., Baker, Suzanne L., Okamura, Nobuyuki, Furukawa, Katsutoshi, Ishiki, Aiko, Furumoto, Shozo, Tashiro, Manabu, Yanai, Kazuhiko, Arai, Hiroyuki, Kudo, Yukitsuka, Harada, Ryuichi, Tomita, Naoki, Hiraoka, Kotaro, Watanuki, Shoichi, Jagust, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927104/
https://ncbi.nlm.nih.gov/pubmed/27355840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158460
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