The development and validation of tau PET tracers: current status and future directions

Por Okamura, Nobuyuki, Harada, Ryuichi, Ishiki, Aiko, Kikuchi, Akio, Nakamura, Tadaho, Kudo, Yukitsuka
Publicado no Clin Transl Imaging (2018)

Characteristics of Tau and Its Ligands in PET Imaging

Por Harada, Ryuichi, Okamura, Nobuyuki, Furumoto, Shozo, Tago, Tetsuro, Yanai, Kazuhiko, Arai, Hiroyuki, Kudo, Yukitsuka
Publicado no Biomolecules (2016)

Synthesis and pharmacokinetic characterisation of a fluorine-18 labelled brain shuttle peptide fusion dimeric affibody

Por Morito, Takahiro, Harada, Ryuichi, Iwata, Ren, Du, Yiqing, Okamura, Nobuyuki, Kudo, Yukitsuka, Yanai, Kazuhiko
Publicado no Sci Rep (2021)

Orengedokuto and san'oshashinto improve memory deficits by inhibiting aging-dependent activation of glycogen synthase kinase-3β

Por Fujiwara, Hironori, Yoshida, Jun, Dibwe, Dya Fita, Awale, Suresh, Hoshino, Haruka, Kohama, Hiroshi, Arai, Hiroyuki, Kudo, Yukitsuka, Matsumoto, Kinzo
Publicado no J Tradit Complement Med (2018)

Evaluation of the biodistribution and radiation dosimetry of the (18)F-labelled amyloid imaging probe [(18)F]FACT in humans

Por Shidahara, Miho, Tashiro, Manabu, Okamura, Nobuyuki, Furumoto, Shozo, Furukawa, Katsutoshi, Watanuki, Shoichi, Hiraoka, Kotaro, Miyake, Masayasu, Iwata, Ren, Tamura, Hajime, Arai, Hiroyuki, Kudo, Yukitsuka, Yanai, Kazuhiko
Publicado em 2013

Regional tau deposition and subregion atrophy of medial temporal structures in early Alzheimer's disease: A combined positron emission tomography/magnetic resonance imaging study

Por Sone, Daichi, Imabayashi, Etsuko, Maikusa, Norihide, Okamura, Nobuyuki, Furumoto, Shozo, Kudo, Yukitsuka, Ogawa, Masayo, Takano, Harumasa, Yokoi, Yuma, Sakata, Masuhiro, Tsukamoto, Tadashi, Kato, Koichi, Matsuda, Hiroshi
Publicado no Alzheimers Dement (Amst) (2017)

Styrylbenzoxazole Derivatives for In Vivo Imaging of Amyloid Plaques in the Brain

Por Okamura, Nobuyuki, Suemoto, Takahiro, Shimadzu, Hiroshi, Suzuki, Masako, Shiomitsu, Tsuyoshi, Akatsu, Hiroyasu, Yamamoto, Takayuki, Staufenbiel, Matthias, Yanai, Kazuhiko, Arai, Hiroyuki, Sasaki, Hidetada, Kudo, Yukitsuka, Sawada, Tohru
Publicado no J Neurosci (2004)

Association of deposition of tau and amyloid‐β proteins with structural connectivity changes in cognitively normal older adults and Alzheimer’s disease spectrum patients

Por Shigemoto, Yoko, Sone, Daichi, Maikusa, Norihide, Okamura, Nobuyuki, Furumoto, Shozo, Kudo, Yukitsuka, Ogawa, Masayo, Takano, Harumasa, Yokoi, Yuma, Sakata, Masuhiro, Tsukamoto, Tadashi, Kato, Koichi, Sato, Noriko, Matsuda, Hiroshi
Publicado no Brain Behav (2018)

Quinoline and Benzimidazole Derivatives: Candidate Probes for In Vivo Imaging of Tau Pathology in Alzheimer's Disease

Por Okamura, Nobuyuki, Suemoto, Takahiro, Furumoto, Shozo, Suzuki, Masako, Shimadzu, Hiroshi, Akatsu, Hiroyasu, Yamamoto, Takayuki, Fujiwara, Hironori, Nemoto, Miyako, Maruyama, Masahiro, Arai, Hiroyuki, Yanai, Kazuhiko, Sawada, Tohru, Kudo, Yukitsuka
Publicado no J Neurosci (2005)

Dissociation of Tau Deposits and Brain Atrophy in Early Alzheimer’s Disease: A Combined Positron Emission Tomography/Magnetic Resonance Imaging Study

Por Shigemoto, Yoko, Sone, Daichi, Imabayashi, Etsuko, Maikusa, Norihide, Okamura, Nobuyuki, Furumoto, Shozo, Kudo, Yukitsuka, Ogawa, Masayo, Takano, Harumasa, Yokoi, Yuma, Sakata, Masuhiro, Tsukamoto, Tadashi, Kato, Koichi, Sato, Noriko, Matsuda, Hiroshi
Publicado no Front Aging Neurosci (2018)

Assessing THK523 selectivity for tau deposits in Alzheimer’s disease and non–Alzheimer’s disease tauopathies

Por Fodero-Tavoletti, Michelle T, Furumoto, Shozo, Taylor, Leanne, McLean, Catriona A, Mulligan, Rachel S, Birchall, Ian, Harada, Ryuichi, Masters, Colin L, Yanai, Kazuhiko, Kudo, Yukitsuka, Rowe, Christopher C, Okamura, Nobuyuki, Villemagne, Victor L
Publicado em 2014

Longitudinal Assessment of Tau Pathology in Patients with Alzheimer’s Disease Using [(18)F]THK-5117 Positron Emission Tomography

Por Ishiki, Aiko, Okamura, Nobuyuki, Furukawa, Katsutoshi, Furumoto, Shozo, Harada, Ryuichi, Tomita, Naoki, Hiraoka, Kotaro, Watanuki, Shoichi, Ishikawa, Yoichi, Tago, Tetsuro, Funaki, Yoshihito, Iwata, Ren, Tashiro, Manabu, Yanai, Kazuhiko, Kudo, Yukitsuka, Arai, Hiroyuki
Publicado no PLoS One (2015)

Cortical Lamina Binding of PET Amyloid and Tau Tracers in Alzheimer's disease

Por Li, Yi, Tsui, Wai, Rusinek, Henry, Butler, Tracy, Mosconi, Lisa, Pirraglia, Elizabeth., Mozley, David, Vallabhajosula, Shankar, Harada, Ryuichi, Furumoto, Shozo, Furukawa, Katsutoshi, Arai, Hiroyuki, Kudo, Yukitsuka, Okamura, Nobuyuki, de Leon, Mony J.
Publicado no J Nucl Med (2015)

Dynamic PET Measures of Tau Accumulation in Cognitively Normal Older Adults and Alzheimer’s Disease Patients Measured Using [18F] THK-5351

Por Lockhart, Samuel N., Baker, Suzanne L., Okamura, Nobuyuki, Furukawa, Katsutoshi, Ishiki, Aiko, Furumoto, Shozo, Tashiro, Manabu, Yanai, Kazuhiko, Arai, Hiroyuki, Kudo, Yukitsuka, Harada, Ryuichi, Tomita, Naoki, Hiraoka, Kotaro, Watanuki, Shoichi, Jagust, William J.
Publicado no PLoS One (2016)

Neuroimaging-pathological correlations of [(18)F]THK5351 PET in progressive supranuclear palsy

Por Ishiki, Aiko, Harada, Ryuichi, Kai, Hideaki, Sato, Naomi, Totsune, Tomoko, Tomita, Naoki, Watanuki, Shoichi, Hiraoka, Kotaro, Ishikawa, Yoichi, Funaki, Yoshihito, Iwata, Ren, Furumoto, Shozo, Tashiro, Manabu, Sasano, Hironobu, Kitamoto, Tetsuyuki, Kudo, Yukitsuka, Yanai, Kazuhiko, Furukawa, Katsutoshi, Okamura, Nobuyuki, Arai, Hiroyuki
Publicado no Acta Neuropathol Commun (2018)

In vivo visualization of tau deposits in corticobasal syndrome by (18)F-THK5351 PET

Por Kikuchi, Akio, Okamura, Nobuyuki, Hasegawa, Takafumi, Harada, Ryuichi, Watanuki, Shoichi, Funaki, Yoshihito, Hiraoka, Kotaro, Baba, Toru, Sugeno, Naoto, Oshima, Ryuji, Yoshida, Shun, Kobayashi, Junpei, Ezura, Michinori, Kobayashi, Michiko, Tano, Ohito, Mugikura, Shunji, Iwata, Ren, Ishiki, Aiko, Furukawa, Katsutoshi, Arai, Hiroyuki, Furumoto, Shozo, Tashiro, Manabu, Yanai, Kazuhiko, Kudo, Yukitsuka, Takeda, Atsushi, Aoki, Masashi
Publicado no Neurology (2016)

Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls

Por Maruyama, Masahiro, Shimada, Hitoshi, Suhara, Tetsuya, Shinotoh, Hitoshi, Ji, Bin, Maeda, Jun, Zhang, Ming-Rong, Trojanowski, John Q., Lee, Virginia M.-Y., Ono, Maiko, Masamoto, Kazuto, Takano, Harumasa, Sahara, Naruhiko, Iwata, Nobuhisa, Okamura, Nobuyuki, Furumoto, Shozo, Kudo, Yukitsuka, Chang, Qiang, Saido, Takaomi C., Takashima, Akihiko, Lewis, Jada, Jang, Ming-Kuei, Aoki, Ichio, Ito, Hiroshi, Higuchi, Makoto
Publicado em 2013