Longitudinal Assessment of Tau Pathology in Patients with Alzheimer’s Disease Using [(18)F]THK-5117 Positron Emission Tomography

The formation of neurofibrillary tangles is believed to contribute to the neurodegeneration observed in Alzheimer’s disease (AD). Postmortem studies have shown strong associations between the neurofibrillary pathology and both neuronal loss and the severity of cognitive impairment. However, the temp...

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Pubblicato in:PLoS One
Autori principali: Ishiki, Aiko, Okamura, Nobuyuki, Furukawa, Katsutoshi, Furumoto, Shozo, Harada, Ryuichi, Tomita, Naoki, Hiraoka, Kotaro, Watanuki, Shoichi, Ishikawa, Yoichi, Tago, Tetsuro, Funaki, Yoshihito, Iwata, Ren, Tashiro, Manabu, Yanai, Kazuhiko, Kudo, Yukitsuka, Arai, Hiroyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604169/
https://ncbi.nlm.nih.gov/pubmed/26461913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140311
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