Longitudinal Assessment of Tau Pathology in Patients with Alzheimer’s Disease Using [(18)F]THK-5117 Positron Emission Tomography

The formation of neurofibrillary tangles is believed to contribute to the neurodegeneration observed in Alzheimer’s disease (AD). Postmortem studies have shown strong associations between the neurofibrillary pathology and both neuronal loss and the severity of cognitive impairment. However, the temp...

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Bibliographic Details
Published in:PLoS One
Main Authors: Ishiki, Aiko, Okamura, Nobuyuki, Furukawa, Katsutoshi, Furumoto, Shozo, Harada, Ryuichi, Tomita, Naoki, Hiraoka, Kotaro, Watanuki, Shoichi, Ishikawa, Yoichi, Tago, Tetsuro, Funaki, Yoshihito, Iwata, Ren, Tashiro, Manabu, Yanai, Kazuhiko, Kudo, Yukitsuka, Arai, Hiroyuki
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604169/
https://ncbi.nlm.nih.gov/pubmed/26461913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140311
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