Subgroups of Paediatric Acute Lymphoblastic Leukaemia Might Differ Significantly in Genetic Predisposition to Asparaginase Hypersensitivity

L-asparaginase (ASP) is a key element in the treatment of paediatric acute lymphoblastic leukaemia (ALL). However, hypersensitivity reactions (HSRs) to ASP are major challenges in paediatric patients. Our aim was to investigate genetic variants that may influence the risk to Escherichia coli-derived...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Kutszegi, Nóra, Semsei, Ágnes F., Gézsi, András, Sági, Judit C., Nagy, Viktória, Csordás, Katalin, Jakab, Zsuzsanna, Lautner-Csorba, Orsolya, Gábor, Krisztina Míta, Kovács, Gábor T., Erdélyi, Dániel J., Szalai, Csaba
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601692/
https://ncbi.nlm.nih.gov/pubmed/26457809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140136
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