Subgroups of Paediatric Acute Lymphoblastic Leukaemia Might Differ Significantly in Genetic Predisposition to Asparaginase Hypersensitivity

L-asparaginase (ASP) is a key element in the treatment of paediatric acute lymphoblastic leukaemia (ALL). However, hypersensitivity reactions (HSRs) to ASP are major challenges in paediatric patients. Our aim was to investigate genetic variants that may influence the risk to Escherichia coli-derived...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kutszegi, Nóra, Semsei, Ágnes F., Gézsi, András, Sági, Judit C., Nagy, Viktória, Csordás, Katalin, Jakab, Zsuzsanna, Lautner-Csorba, Orsolya, Gábor, Krisztina Míta, Kovács, Gábor T., Erdélyi, Dániel J., Szalai, Csaba
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601692/
https://ncbi.nlm.nih.gov/pubmed/26457809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140136
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