Subgroups of Paediatric Acute Lymphoblastic Leukaemia Might Differ Significantly in Genetic Predisposition to Asparaginase Hypersensitivity

L-asparaginase (ASP) is a key element in the treatment of paediatric acute lymphoblastic leukaemia (ALL). However, hypersensitivity reactions (HSRs) to ASP are major challenges in paediatric patients. Our aim was to investigate genetic variants that may influence the risk to Escherichia coli-derived...

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Pubblicato in:PLoS One
Autori principali: Kutszegi, Nóra, Semsei, Ágnes F., Gézsi, András, Sági, Judit C., Nagy, Viktória, Csordás, Katalin, Jakab, Zsuzsanna, Lautner-Csorba, Orsolya, Gábor, Krisztina Míta, Kovács, Gábor T., Erdélyi, Dániel J., Szalai, Csaba
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601692/
https://ncbi.nlm.nih.gov/pubmed/26457809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140136
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