In vitro neutralization of prions with PrP(Sc)-specific antibodies

Prion diseases reflect the misfolding of a self-protein (PrP(C)) into an infectious, pathological isomer (PrP(Sc)). By targeting epitopes uniquely exposed by misfolding, our group developed PrP(Sc)-specific vaccines to 3 disease specific epitopes (DSEs). Here, antibodies induced by individual DSE va...

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Vydáno v:Prion
Hlavní autoři: Taschuk, Ryan, Van der Merwe, Jacques, Marciniuk, Kristen, Potter, Andrew, Cashman, Neil, Griebel, Philip, Napper, Scott
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601508/
https://ncbi.nlm.nih.gov/pubmed/26284508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1071761
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