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In vitro neutralization of prions with PrP(Sc)-specific antibodies
Prion diseases reflect the misfolding of a self-protein (PrP(C)) into an infectious, pathological isomer (PrP(Sc)). By targeting epitopes uniquely exposed by misfolding, our group developed PrP(Sc)-specific vaccines to 3 disease specific epitopes (DSEs). Here, antibodies induced by individual DSE va...
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| Veröffentlicht in: | Prion |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601508/ https://ncbi.nlm.nih.gov/pubmed/26284508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1071761 |
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