Safety, specificity and immunogenicity of a PrP(Sc)-specific prion vaccine based on the YYR disease specific epitope

Prions are a novel form of infectivity based on the misfolding of a self-protein (PrP(C)) into a pathological, infectious isomer (PrP(Sc)). The current uncontrolled spread of chronic wasting disease in cervids, coupled with the demonstrated zoonotic nature of select livestock prion diseases, highlig...

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Detalhes bibliográficos
Publicado no:Prion
Main Authors: Taschuk, Ryan, Marciniuk, Kristen, Määttänen, Pekka, Madampage, Claudia, Hedlin, Peter, Potter, Andrew, Lee, Jeremy, Cashman, Neil R., Griebel, Philip J, Napper, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030909/
https://ncbi.nlm.nih.gov/pubmed/24509522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.27962
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