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Binding of bovine T194A PrP(C) by PrP(Sc)-specific antibodies: Potential implications for immunotherapy of familial prion diseases
Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases that are based on the misfolding of a cellular prion protein (PrP(C)) into an infectious, pathological conformation (PrP(Sc)). There is proof-of-principle evidence that a prion vaccine is possible but this is tempe...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904316/ https://ncbi.nlm.nih.gov/pubmed/23787697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.25148 |
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