In vitro neutralization of prions with PrP(Sc)-specific antibodies

Prion diseases reflect the misfolding of a self-protein (PrP(C)) into an infectious, pathological isomer (PrP(Sc)). By targeting epitopes uniquely exposed by misfolding, our group developed PrP(Sc)-specific vaccines to 3 disease specific epitopes (DSEs). Here, antibodies induced by individual DSE va...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Prion
Prif Awduron: Taschuk, Ryan, Van der Merwe, Jacques, Marciniuk, Kristen, Potter, Andrew, Cashman, Neil, Griebel, Philip, Napper, Scott
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601508/
https://ncbi.nlm.nih.gov/pubmed/26284508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1071761
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