Llwytho...
Pressure-assisted dissociation and degradation of “proteinase K-resistant” fibrils prepared by seeding with scrapie-infected hamster prion protein
The crucial step for the fatal neurodegenerative prion diseases involves the conversion of a normal cellular protein, PrP(C), into a fibrous pathogenic form, PrP(Sc), which has an unusual stability against heat and resistance against proteinase K digestion. A successful challenge to reverse the reac...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Prion |
---|---|
Prif Awduron: | , , , , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Taylor & Francis
2014
|
Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601478/ https://ncbi.nlm.nih.gov/pubmed/25482603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.32081 |
Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|