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Regulating extracellular proteostasis capacity through the unfolded protein response

The extracellular aggregation of proteins into proteotoxic oligomers and amyloid fibrils is implicated in the onset and pathology of numerous diseases referred to as amyloid diseases. All of the proteins that aggregate extracellularly in association with amyloid disease pathogenesis originate in the...

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Pubblicato in:Prion
Autori principali: Genereux, Joseph C, Wiseman, R Luke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601297/
https://ncbi.nlm.nih.gov/pubmed/25946012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1011887
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