Mitoenergetic Dysfunction Triggers a Rapid Compensatory Increase in Steady-State Glucose Flux

ATP can be produced in the cytosol by glycolytic conversion of glucose (GLC) into pyruvate. The latter can be metabolized into lactate, which is released by the cell, or taken up by mitochondria to fuel ATP production by the tricarboxylic acid cycle and oxidative phosphorylation (OXPHOS) system. Alt...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Liemburg-Apers, Dania C., Schirris, Tom J.J., Russel, Frans G.M., Willems, Peter H.G.M., Koopman, Werner J.H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2015
Soggetti:
Cell Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601044/
https://ncbi.nlm.nih.gov/pubmed/26445438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.002
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