Mitoenergetic Dysfunction Triggers a Rapid Compensatory Increase in Steady-State Glucose Flux

ATP can be produced in the cytosol by glycolytic conversion of glucose (GLC) into pyruvate. The latter can be metabolized into lactate, which is released by the cell, or taken up by mitochondria to fuel ATP production by the tricarboxylic acid cycle and oxidative phosphorylation (OXPHOS) system. Alt...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Liemburg-Apers, Dania C., Schirris, Tom J.J., Russel, Frans G.M., Willems, Peter H.G.M., Koopman, Werner J.H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Cell Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601044/
https://ncbi.nlm.nih.gov/pubmed/26445438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.002
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