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Mitoenergetic Dysfunction Triggers a Rapid Compensatory Increase in Steady-State Glucose Flux
ATP can be produced in the cytosol by glycolytic conversion of glucose (GLC) into pyruvate. The latter can be metabolized into lactate, which is released by the cell, or taken up by mitochondria to fuel ATP production by the tricarboxylic acid cycle and oxidative phosphorylation (OXPHOS) system. Alt...
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| izdano v: | Biophys J |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601044/ https://ncbi.nlm.nih.gov/pubmed/26445438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.002 |
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