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A probabilistic model of human variability in physiology for future application to dose reconstruction and QIVIVE

The risk assessment of environmental chemicals and drugs is undergoing a paradigm shift in approach which seeks the full replacement of animal testing with high throughput, mechanistic, in vitro systems. This new approach will be reliant on the measurement in vitro, of concentration-dependent respon...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Principais autores: McNally, Kevin, Loizou, George D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600921/
https://ncbi.nlm.nih.gov/pubmed/26528180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00213
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