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Derivation of LIF-independent mouse iPS cells with modified Oct4

It has been very difficult, if not impossible, to establish mouse induced pluripotent stem cells (iPSCs) from differentiated cells, such as fibroblasts, without leukemia inhibitory factor (LIF). We have established and maintained LIF-independent iPSCs for longer than 120 days with modified Oct4 alon...

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Res
Hauptverfasser: Hirai, Hiroyuki, Firpo, Meri, Kikyo, Nobuaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600661/
https://ncbi.nlm.nih.gov/pubmed/26318720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2015.08.005
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