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Establishment of LIF-Dependent Human iPS Cells Closely Related to Basic FGF-Dependent Authentic iPS Cells

Human induced pluripotent stem cells (iPSCs) can be divided into a leukemia inhibitory factor (LIF)-dependent naïve type and a basic fibroblast growth factor (bFGF)-dependent primed type. Although the former are more undifferentiated than the latter, they require signal transduction inhibitors and s...

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Detalhes bibliográficos
Main Authors: Hirai, Hiroyuki, Firpo, Meri, Kikyo, Nobuaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374774/
https://ncbi.nlm.nih.gov/pubmed/22720020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039022
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