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Derivation of LIF-independent mouse iPS cells with modified Oct4

It has been very difficult, if not impossible, to establish mouse induced pluripotent stem cells (iPSCs) from differentiated cells, such as fibroblasts, without leukemia inhibitory factor (LIF). We have established and maintained LIF-independent iPSCs for longer than 120 days with modified Oct4 alon...

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Bibliografiska uppgifter
I publikationen:Stem Cell Res
Huvudupphovsmän: Hirai, Hiroyuki, Firpo, Meri, Kikyo, Nobuaki
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600661/
https://ncbi.nlm.nih.gov/pubmed/26318720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2015.08.005
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