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Derivation of LIF-independent mouse iPS cells with modified Oct4

It has been very difficult, if not impossible, to establish mouse induced pluripotent stem cells (iPSCs) from differentiated cells, such as fibroblasts, without leukemia inhibitory factor (LIF). We have established and maintained LIF-independent iPSCs for longer than 120 days with modified Oct4 alon...

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Detalhes bibliográficos
Publicado no:Stem Cell Res
Main Authors: Hirai, Hiroyuki, Firpo, Meri, Kikyo, Nobuaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600661/
https://ncbi.nlm.nih.gov/pubmed/26318720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2015.08.005
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