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Establishment of LIF-dependent human iPS cells closely related to basic FGF-dependent authentic iPS cells.

Human induced pluripotent stem cells (iPSCs) can be divided into a leukemia inhibitory factor (LIF)-dependent naïve type and a basic fibroblast growth factor (bFGF)-dependent primed type. Although the former are more undifferentiated than the latter, they require signal transduction inhibitors and s...

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Autores principales: Hiroyuki Hirai, Meri Firpo, Nobuaki Kikyo
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2012-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC3374774?pdf=render
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