Establishment of LIF-dependent human iPS cells closely related to basic FGF-dependent authentic iPS cells.

Human induced pluripotent stem cells (iPSCs) can be divided into a leukemia inhibitory factor (LIF)-dependent naïve type and a basic fibroblast growth factor (bFGF)-dependent primed type. Although the former are more undifferentiated than the latter, they require signal transduction inhibitors and s...

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Main Authors: Hiroyuki Hirai, Meri Firpo, Nobuaki Kikyo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2012-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC3374774?pdf=render
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