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Derivation of LIF-independent mouse iPS cells with modified Oct4

It has been very difficult, if not impossible, to establish mouse induced pluripotent stem cells (iPSCs) from differentiated cells, such as fibroblasts, without leukemia inhibitory factor (LIF). We have established and maintained LIF-independent iPSCs for longer than 120 days with modified Oct4 alon...

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Détails bibliographiques
Publié dans:Stem Cell Res
Auteurs principaux: Hirai, Hiroyuki, Firpo, Meri, Kikyo, Nobuaki
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600661/
https://ncbi.nlm.nih.gov/pubmed/26318720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2015.08.005
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