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Conformational dynamics of a class C G protein-coupled receptor

G protein-coupled receptors (GPCRs) constitute the largest family of membrane receptors in eukaryotes. Crystal structures have provided insight into GPCR interaction with ligands and G-proteins(1,2), but our understanding of the conformational dynamics of activation is incomplete. Metabotropic gluta...

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書目詳細資料
發表在:Nature
Main Authors: Vafabakhsh, Reza, Levitz, Joshua, Isacoff, Ehud Y.
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597782/
https://ncbi.nlm.nih.gov/pubmed/26258295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14679
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