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Mechanism of assembly and cooperativity of homomeric and heteromeric metabotropic glutamate receptors

G protein-coupled receptors (GPCRs) mediate cellular responses to a wide variety of extracellular stimuli. GPCR dimerization may expand signaling diversity and tune functionality, but little is known about the mechanisms of subunit assembly and interaction or the signaling properties of heteromers....

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Dades bibliogràfiques
Publicat a:Neuron
Autors principals: Levitz, Joshua, Habrian, Chris, Bharill, Shashank, Fu, Zhu, Vafabakhsh, Reza, Isacoff, Ehud Y.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053906/
https://ncbi.nlm.nih.gov/pubmed/27641494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.08.036
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