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Mechanism of assembly and cooperativity of homomeric and heteromeric metabotropic glutamate receptors

G protein-coupled receptors (GPCRs) mediate cellular responses to a wide variety of extracellular stimuli. GPCR dimerization may expand signaling diversity and tune functionality, but little is known about the mechanisms of subunit assembly and interaction or the signaling properties of heteromers....

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Levitz, Joshua, Habrian, Chris, Bharill, Shashank, Fu, Zhu, Vafabakhsh, Reza, Isacoff, Ehud Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053906/
https://ncbi.nlm.nih.gov/pubmed/27641494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.08.036
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