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Conformational dynamics of a class C G protein-coupled receptor
G protein-coupled receptors (GPCRs) constitute the largest family of membrane receptors in eukaryotes. Crystal structures have provided insight into GPCR interaction with ligands and G-proteins(1,2), but our understanding of the conformational dynamics of activation is incomplete. Metabotropic gluta...
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| Veröffentlicht in: | Nature |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4597782/ https://ncbi.nlm.nih.gov/pubmed/26258295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14679 |
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