A High Through-put Platform for Recombinant Antibodies to Folded Proteins

Antibodies are key reagents in biology and medicine, but commercial sources are rarely recombinant and thus do not provide a permanent and renewable resource. Here, we describe an industrialized platform to generate antigens and validated recombinant antibodies for 346 transcription factors (TFs) an...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Hornsby, Michael, Paduch, Marcin, Miersch, Shane, Sääf, Annika, Matsuguchi, Tet, Lee, Brian, Wypisniak, Karolina, Doak, Allison, King, Daniel, Usatyuk, Svitlana, Perry, Kimberly, Lu, Vince, Thomas, William, Luke, Judy, Goodman, Jay, Hoey, Robert J., Lai, Darson, Griffin, Carly, Li, Zhijian, Vizeacoumar, Franco J., Dong, Debbie, Campbell, Elliot, Anderson, Stephen, Zhong, Nan, Gräslund, Susanne, Koide, Shohei, Moffat, Jason, Sidhu, Sachdev, Kossiakoff, Anthony, Wells, James
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2015
Subjects:
Technological Innovations and Resources
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597156/
https://ncbi.nlm.nih.gov/pubmed/26290498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O115.052209
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