A High Through-put Platform for Recombinant Antibodies to Folded Proteins

Antibodies are key reagents in biology and medicine, but commercial sources are rarely recombinant and thus do not provide a permanent and renewable resource. Here, we describe an industrialized platform to generate antigens and validated recombinant antibodies for 346 transcription factors (TFs) an...

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Bibliografske podrobnosti
izdano v:Mol Cell Proteomics
Main Authors: Hornsby, Michael, Paduch, Marcin, Miersch, Shane, Sääf, Annika, Matsuguchi, Tet, Lee, Brian, Wypisniak, Karolina, Doak, Allison, King, Daniel, Usatyuk, Svitlana, Perry, Kimberly, Lu, Vince, Thomas, William, Luke, Judy, Goodman, Jay, Hoey, Robert J., Lai, Darson, Griffin, Carly, Li, Zhijian, Vizeacoumar, Franco J., Dong, Debbie, Campbell, Elliot, Anderson, Stephen, Zhong, Nan, Gräslund, Susanne, Koide, Shohei, Moffat, Jason, Sidhu, Sachdev, Kossiakoff, Anthony, Wells, James
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2015
Teme:
Technological Innovations and Resources
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597156/
https://ncbi.nlm.nih.gov/pubmed/26290498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O115.052209
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