A High Through-put Platform for Recombinant Antibodies to Folded Proteins

Antibodies are key reagents in biology and medicine, but commercial sources are rarely recombinant and thus do not provide a permanent and renewable resource. Here, we describe an industrialized platform to generate antigens and validated recombinant antibodies for 346 transcription factors (TFs) an...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Hornsby, Michael, Paduch, Marcin, Miersch, Shane, Sääf, Annika, Matsuguchi, Tet, Lee, Brian, Wypisniak, Karolina, Doak, Allison, King, Daniel, Usatyuk, Svitlana, Perry, Kimberly, Lu, Vince, Thomas, William, Luke, Judy, Goodman, Jay, Hoey, Robert J., Lai, Darson, Griffin, Carly, Li, Zhijian, Vizeacoumar, Franco J., Dong, Debbie, Campbell, Elliot, Anderson, Stephen, Zhong, Nan, Gräslund, Susanne, Koide, Shohei, Moffat, Jason, Sidhu, Sachdev, Kossiakoff, Anthony, Wells, James
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Technological Innovations and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597156/
https://ncbi.nlm.nih.gov/pubmed/26290498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O115.052209
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