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Force-regulated in situ TCR–pMHC-II kinetics determine functions of CD4(+) T cells
We have recently shown that two-dimensional (2D) and force-regulated kinetics of TCR–pMHC-I interactions predict responses of CD8(+) T cells. To test whether these findings are applicable to CD4(+) T cells, we analyzed the in situ 3.L2 TCR–pMHC-II interactions for a well-characterized panel of alter...
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| Izdano u: | J Immunol |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4592802/ https://ncbi.nlm.nih.gov/pubmed/26336148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501407 |
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