2D TCR–pMHC–CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system

Two-dimensional (2D) kinetic analysis directly measures molecular interactions at cell-cell junctions, thereby incorporating inherent cellular effects. By comparison, three-dimensional (3D) analysis probes the intrinsic physical chemistry of interacting molecules isolated from the cell. To understan...

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Main Authors: Liu, Baoyu, Zhong, Shi, Malecek, Karolina, Johnson, Laura A, Rosenberg, Steven A., Zhu, Cheng, Krogsgaard, Michelle
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941036/
https://ncbi.nlm.nih.gov/pubmed/24114747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343774
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