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Accumulation of serial forces on TCR and CD8 frequently applied by agonist pMHC triggers calcium in T cell

T cell activation by antigen is one of the key events in adaptive immunity. It is triggered by interactions of the T-cell receptor (TCR) and coreceptor (CD8 or CD4) with antigenic peptides embedded in the major histocompatibility complex (pMHC) molecules expressed on antigen presenting cells (APCs)....

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Détails bibliographiques
Auteurs principaux: Pryshchep, Sergey, Zarnitsyna, Veronika I., Hong, Jinsung, Evavold, Brian D., Zhu, Cheng
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090054/
https://ncbi.nlm.nih.gov/pubmed/24890718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303436
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