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Accumulation of serial forces on TCR and CD8 frequently applied by agonist pMHC triggers calcium in T cell
T cell activation by antigen is one of the key events in adaptive immunity. It is triggered by interactions of the T-cell receptor (TCR) and coreceptor (CD8 or CD4) with antigenic peptides embedded in the major histocompatibility complex (pMHC) molecules expressed on antigen presenting cells (APCs)....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4090054/ https://ncbi.nlm.nih.gov/pubmed/24890718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303436 |
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