The Capsule Polymerase CslB of Neisseria meningitidis Serogroup L Catalyzes the Synthesis of a Complex Trimeric Repeating Unit Comprising Glycosidic and Phosphodiester Linkages

Neisseria meningitidis is a human pathogen causing bacterial meningitis and sepsis. The capsular polysaccharide surrounding N. meningitidis is a major virulence factor. The capsular polysaccharide consists of polyhexosamine phosphates in N. meningitidis serogroups A and X. The capsule polymerases (C...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Litschko, Christa, Romano, Maria Rosaria, Pinto, Vittoria, Claus, Heike, Vogel, Ulrich, Berti, Francesco, Gerardy-Schahn, Rita, Fiebig, Timm
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591819/
https://ncbi.nlm.nih.gov/pubmed/26286750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678094
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