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Biochemical and Biophysical Characterization of the Sialyl-/Hexosyltransferase Synthesizing the Meningococcal Serogroup W135 Heteropolysaccharide Capsule

Neisseria meningitidis (Nm) is a leading cause of bacterial meningitis and sepsis. Crucial virulence determinants of pathogenic Nm strains are the polysaccharide capsules that support invasion by hindering complement attack. In NmW-135 and NmY the capsules are built from the repeating units (→6)-α-d...

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Bibliografski detalji
Glavni autori: Romanow, Angela, Haselhorst, Thomas, Stummeyer, Katharina, Claus, Heike, Bethe, Andrea, Mühlenhoff, Martina, Vogel, Ulrich, von Itzstein, Mark, Gerardy-Schahn, Rita
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636861/
https://ncbi.nlm.nih.gov/pubmed/23439648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.452276
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