Efficient solid-phase synthesis of meningococcal capsular oligosaccharides enables simple and fast chemoenzymatic vaccine production

Neisseria meningitidis serogroups A and X are among the leading causes of bacterial meningitis in the African meningitis belt. Glycoconjugate vaccines, consisting of an antigenic carrier protein coupled to the capsular polysaccharide of the bacterial pathogen, are the most effective strategy for pre...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Fiebig, Timm, Litschko, Christa, Freiberger, Friedrich, Bethe, Andrea, Berger, Monika, Gerardy-Schahn, Rita
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2018
Ämnen:
Glycobiology and Extracellular Matrices
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777266/
https://ncbi.nlm.nih.gov/pubmed/29187601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000488
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