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An enzyme-based protocol for cell-free synthesis of nature-identical capsular oligosaccharides from Actinobacillus pleuropneumoniae serotype 1

Actinobacillus pleuropneumoniae (App) is the etiological agent of acute porcine pneumonia and responsible for severe economic losses worldwide. The capsule polymer of App serotype 1 (App1) consists of [4)-GlcNAc-β(1,6)-Gal-α-1-(PO(4)-] repeating units that are O-acetylated at O-6 of the GlcNAc. It i...

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Foilsithe in:J Biol Chem
Main Authors: Budde, Insa, Litschko, Christa, Führing, Jana I, Gerardy-Schahn, Rita, Schubert, Mario, Fiebig, Timm
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186170/
https://ncbi.nlm.nih.gov/pubmed/32152227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012961
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