CONSERTING: integrating copy number analysis with structural variation detection

We developed Copy Number Segmentation by Regression Tree in Next Generation Sequencing (CONSERTING), a novel algorithm for detecting somatic copy number alteration (CNA) using whole-genome sequencing (WGS) data. CONSERTING performs iterative analysis of segmentation by read depth change and localize...

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Publicado no:Nat Methods
Main Authors: Chen, Xiang, Gupta, Pankaj, Wang, Jianmin, Nakitandwe, Joy, Roberts, Kathryn, Dalton, James D., Parker, Matthew, Patel, Samir, Holmfeldt, Linda, Payne, Debbie, Easton, John, Ma, Jing, Rusch, Michael, Wu, Gang, Patel, Aman, J. Baker, Suzanne, Dyer, Michael A., Shurtleff, Sheila, Espy, Stephen, Pounds, Stanley, Downing, James R., Ellison, David W., Mullighan, Charles G., Zhang, Jinghui
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591043/
https://ncbi.nlm.nih.gov/pubmed/25938371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3394
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