CREST maps somatic structural variation in cancer genomes with base-pair resolution

We developed CREST (Clipping REveals STructure), an algorithm that uses next-generation sequencing reads with partial alignments to a reference genome to directly map structural variations at the nucleotide level of resolution. Application of CREST to whole-genome sequencing data from five pediatric...

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Main Authors: Wang, Jianmin, Mullighan, Charles G., Easton, John, Roberts, Stefan, Ma, Jing, Rusch, Michael C., Chen, Ken, Harris, Christopher C., Ding, Li, Heatley, Sue L., Holmfeldt, Linda, Payne-Turner, Debbie, Fan, Xian, Wei, Lei, Zhao, David, Obenauer, John C., Naeve, Clayton, Mardis, Elaine R., Wilson, Richard K., Downing, James R., Zhang, Jinghui
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527068/
https://ncbi.nlm.nih.gov/pubmed/21666668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1628
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