Wordt geladen...

Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner

Mechanistic target of rapamycin (serine/threonine kinase) complex 1 (MTORC1) is a protein-signaling complex at the fulcrum of anabolic and catabolic processes, which acts depending on wide-ranging environmental cues. It is generally accepted that lysosomes facilitate MTORC1 activation by generating...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Autophagy
Hoofdauteurs: Newton, Phillip T, Vuppalapati, Karuna K, Bouderlique, Thibault, Chagin, Andrei S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590675/
https://ncbi.nlm.nih.gov/pubmed/26259639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1068489
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!