Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy

Autophagy represents an intracellular degradation process which is involved in both regular cell homeostasis and disease settings. In recent years, the molecular machinery governing this process has been elucidated. The ULK1 kinase complex consisting of the serine/threonine protein kinase ULK1 and t...

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Библиографические подробности
Опубликовано в: :Autophagy
Главные авторы: Drießen, Stefan, Berleth, Niklas, Friesen, Olena, Löffler, Antje S, Böhler, Philip, Hieke, Nora, Stuhldreier, Fabian, Peter, Christoph, Schink, Kay O, Schultz, Sebastian W, Stenmark, Harald, Holland, Petter, Simonsen, Anne, Wesselborg, Sebastian, Stork, Björn
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2015
Предметы:
Basic Brief Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590650/
https://ncbi.nlm.nih.gov/pubmed/26207339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1067359
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