Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells

Autophagy describes an intracellular process responsible for the lysosome-dependent degradation of cytosolic components. The ULK1/2 complex comprising the kinase ULK1/2 and the accessory proteins ATG13, RB1CC1, and ATG101 has been identified as a central player in the autophagy network, and it repre...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Hieke, Nora, Löffler, Antje S, Kaizuka, Takeshi, Berleth, Niklas, Böhler, Philip, Drießen, Stefan, Stuhldreier, Fabian, Friesen, Olena, Assani, Kaivon, Schmitz, Katharina, Peter, Christoph, Diedrich, Britta, Dengjel, Jörn, Holland, Petter, Simonsen, Anne, Wesselborg, Sebastian, Mizushima, Noboru, Stork, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Basic Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590663/
https://ncbi.nlm.nih.gov/pubmed/26213203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1068488
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