The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

Autophagy is induced during differentiation of human monocytes into macrophages that is mediated by CSF1/CSF-1/M-CSF (colony stimulating factor 1 [macrophage]). However, little is known about the molecular mechanisms that link CSF1 receptor engagement to the induction of autophagy. Here we show that...

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Publicado en:Autophagy
Autores principales: Obba, Sandrine, Hizir, Zoheir, Boyer, Laurent, Selimoglu-Buet, Dorothée, Pfeifer, Anja, Michel, Gregory, Hamouda, Mohamed-Amine, Gonçalvès, Diogo, Cerezo, Michael, Marchetti, Sandrine, Rocchi, Stephane, Droin, Nathalie, Cluzeau, Thomas, Robert, Guillaume, Luciano, Frederic, Robaye, Bernard, Foretz, Marc, Viollet, Benoit, Legros, Laurence, Solary, Eric, Auberger, Patrick, Jacquel, Arnaud
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
Materias:
Basic Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590592/
https://ncbi.nlm.nih.gov/pubmed/26029847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1034406
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