Cytokine-like protein 1–induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML

Mouse models of chronic myeloid malignancies suggest that targeting mature cells of the malignant clone disrupts feedback loops that promote disease expansion. Here, we show that in chronic myelomonocytic leukemia (CMML), monocytes that accumulate in the peripheral blood show a decreased propensity...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Sevin, Margaux, Debeurme, Franck, Laplane, Lucie, Badel, Séverine, Morabito, Margot, Newman, Hanna L., Torres-Martin, Miguel, Yang, Qin, Badaoui, Bouchra, Wagner-Ballon, Orianne, Saada, Véronique, Sélimoglu-Buet, Dorothée, Kraus-Berthier, Laurence, Banquet, Sébastien, Derreal, Alix, Fenaux, Pierre, Itzykson, Raphael, Braun, Thorsten, Etienne, Gabriel, Berthon, Celine, Thépot, Sylvain, Kepp, Oliver, Kroemer, Guido, Padron, Eric, Figueroa, Maria E., Droin, Nathalie, Solary, Eric
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2021
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233685/
https://ncbi.nlm.nih.gov/pubmed/33690800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020008729
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