Cytokine-like protein 1–induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML

Mouse models of chronic myeloid malignancies suggest that targeting mature cells of the malignant clone disrupts feedback loops that promote disease expansion. Here, we show that in chronic myelomonocytic leukemia (CMML), monocytes that accumulate in the peripheral blood show a decreased propensity...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Sevin, Margaux, Debeurme, Franck, Laplane, Lucie, Badel, Séverine, Morabito, Margot, Newman, Hanna L., Torres-Martin, Miguel, Yang, Qin, Badaoui, Bouchra, Wagner-Ballon, Orianne, Saada, Véronique, Sélimoglu-Buet, Dorothée, Kraus-Berthier, Laurence, Banquet, Sébastien, Derreal, Alix, Fenaux, Pierre, Itzykson, Raphael, Braun, Thorsten, Etienne, Gabriel, Berthon, Celine, Thépot, Sylvain, Kepp, Oliver, Kroemer, Guido, Padron, Eric, Figueroa, Maria E., Droin, Nathalie, Solary, Eric
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2021
Konular:
Myeloid Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233685/
https://ncbi.nlm.nih.gov/pubmed/33690800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020008729
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