Engraftment of chronic myelomonocytic leukemia cells in immunocompromised mice supports disease dependency on cytokines

Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder that typically associates with mutations in epigenetic, splicing, and signaling genes. Genetically modified mouse models only partially recapitulate the disease phenotype, whereas xenotransplantation of CMML cells in...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Zhang, Yanyan, He, Liang, Selimoglu-Buet, Dorothée, Jego, Chloe, Morabito, Margot, Willekens, Christophe, Diop, M'boyba Khadija, Gonin, Patrick, Lapierre, Valérie, Droin, Nathalie, Solary, Eric, Louache, Fawzia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737594/
https://ncbi.nlm.nih.gov/pubmed/29296739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017004903
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