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Proper macrophagic differentiation requires both autophagy and caspase activation

Autophagy allows the elimination of superfluous or damaged macromolecules or organelles. Genetic evidence indicates that autophagy plays essential functions during differentiation. The differentiation of human blood monocytes into macrophages is a caspase-dependent process triggered by colony stimul...

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Detalhes bibliográficos
Main Authors: Jacquel, Arnaud, Obba, Sandrine, Solary, Eric, Auberger, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429551/
https://ncbi.nlm.nih.gov/pubmed/22751215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20367
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